Myoclonin1 modulates the post-translational modification of microtubules
نویسندگان
چکیده
منابع مشابه
Barium modulates c-fos expression and post-translational modification.
The addition of exogenous barium ions to PC12 rat pheochromocytoma cells elicits a transient induction of the c-fos gene. Induction is antagonized by extracellular calcium and the dihydropyridine calcium channel blockers, and it is attenuated in the presence of calmodulin inhibitors. Thus, barium appears to enter the cell through a voltage-dependent calcium channel and, either directly or indir...
متن کاملBug22 influences cilium morphology and the post-translational modification of ciliary microtubules
Cilia and flagella are organelles essential for motility and sensing of environmental stimuli. Depending on the cell type, cilia acquire a defined set of functions and, accordingly, are built with an appropriate length and molecular composition. Several ciliary proteins display a high degree of conservation throughout evolution and mutations in ciliary genes are associated with various diseases...
متن کاملAllosteric post-translational modification codes.
Post-translational modifications (PTMs) have been recognized to impact protein function in two ways: (i) orthosterically, via direct recognition by protein domains or through interference with binding; and (ii) allosterically, via conformational changes induced at the functional sites. Because different chemical types of PTMs elicit different structural alterations, the effects of combinatorial...
متن کاملPost-translational modification by SUMO.
Post-translational modifications (PTMs) are chemical alterations to a protein following translation, regulating stability and function. Reversible phosphorylation is an example of an important and well studied PTM involved in a number of cellular processes. SUMOylation is another PTM known to modify a large number of proteins and plays a role in various cellular processes including: cell cycle ...
متن کاملGlobal Post-Translational Modification Discovery
A new global post-translational modification (PTM) discovery strategy, G-PTM-D, is described. A proteomics database containing UniProt-curated PTM information is supplemented with potential new modification types and sites discovered from a first-round search of mass spectrometry data with ultrawide precursor mass tolerance. A second-round search employing the supplemented database conducted wi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2015
ISSN: 1662-453X
DOI: 10.3389/conf.fnins.2015.89.00015